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VAGINAL GLYCOGEN ASSAY FOR OESTROGEN: SPECIFICITY AND APPLICATION TO BLOOD AND URINE

Summary.: A new micro-bio-assay method involving the increase of vaginal glycogen in response to local administration has been used to determine the oestrogenic content of urine and blood. In addition, various other steroid hormones (progesterone, cortisol, desoxycorticosterone, testosterone) were given to test the specificity of the assay. In no instance did the other hormones elicit a glycogen response when given alone, nor did they enhance the response when given in combination with oestrogen.