Reproduction   citetrack
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS  
Reproduction (2002) 123 143-153
DOI: 10.1530/rep.0.1230143
Copyright © 2002 Society for Reproduction and Fertility
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Mattiske, D
Right arrow Articles by Shaw, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mattiske, D
Right arrow Articles by Shaw, J.

Articles

Influence of donor age on development of gonadal tissue from pouch young of the tammar wallaby, Macropus eugenii, after cryopreservation and xenografting into mice

D Mattiske, G Shaw, and JM Shaw

Ovaries from a marsupial, the tammar wallaby (Macropus eugenii), were grafted into a eutherian recipient at known stages of development to ascertain whether normal development would occur. Xenografted ovaries from pouch young < 20 days old, before the onset of meiosis, retained few germ cells and developed tubule-like structures reminiscent of seminiferous cords. Ovaries from 50-day-old pouch young, which contain primordial follicles, developed into antral follicles and corpora lutea within the eutherian host, and produced hormones that stimulated the reproductive tract of the host. The timing of onset of antrum formation and the progress of follicle development were advanced relative to the timing of events in ovaries in situ. Frozen-thawed ovaries from 50-day-old donors developed into preantral follicles, but at a reduced rate and number. This finding shows that gonads of a marsupial species can develop as xenografts in a eutherian, forming large antral follicles. Accelerated follicular development in xenografts provides a potentially valuable model for studying the factors that control follicle development. Assisted reproduction of endangered marsupials may also be feasible using follicles from pouch young grown as xenografts in a eutherian host.


This article has been cited by other articles:


Home page
 ReproductionHome page
H. Kaneko, K. Kikuchi, J. Noguchi, M. Ozawa, K. Ohnuma, N. Maedomari, and N. Kashiwazaki
Effects of gonadotrophin treatments on meiotic and developmental competence of oocytes in porcine primordial follicles following xenografting to nude mice
Reproduction, February 1, 2006; 131(2): 279 - 288.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
H. Kaneko, K. Kikuchi, J. Noguchi, M. Hosoe, and T. Akita
Maturation and Fertilization of Porcine Oocytes from Primordial Follicles by a Combination of Xenografting and In Vitro Culture
Biol Reprod, November 1, 2003; 69(5): 1488 - 1493.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
M. Snow, S.-L. Cox, G. Jenkin, A. Trounson, and J. Shaw
Generation of Live Young from Xenografted Mouse Ovaries
Science, September 27, 2002; 297(5590): 2227 - 2227.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS  
Copyright © 2002 by the Society for Reproduction and Fertility.